Vitamin B12 and What You Need to Know
Vitamin B12 is essential for good health, but some people may not be getting enough. This article tells you about symptoms of a vitamin B12 deficiency and how it can be treated.
How Much do you Need?
The answer depends on things including your age, your eating habits and medical conditions, and what medications you take.
The average recommended amounts, measured in micrograms (mcg), vary by age:
- Infants up to age 6 months: 0.4 mcg
- Babies age 7-12 months: 0.5 mcg
- Children age 1-3 years: 0.9 mcg
- Kids age 4-8 years: 1.2 mcg
- Children age 9-13 years: 1.8 mcg
- Teens age 14-18: 2.4 mcg (2.6 mcg per day if pregnant and 2.8 mcg per day if breastfeeding)
- Adults: 2.4 mcg (2.6 mcg per day if pregnant and 2.8 mcg per day if breastfeeding)
- Older adults may need much more.
Vitamin B12 Deficiency
Symptoms of vitamin B12 or folate deficiency
- extreme tiredness
- a lack of energy
- pins and needles (paraesthesia)
- a sore and red tongue
- mouth ulcers
- muscle weakness
- disturbed vision
- psychological problems, which may include depression and confusion
- problems with memory, understanding and judgement
Some of these problems can also happen if you have a deficiency in vitamin B12 or folate but do not have anaemia.
Causes of a vitamin B12 or folate deficiency
- pernicious anaemia – where your immune system attacks healthy cells in your stomach, preventing your body absorbing vitamin B12 from the food you eat; this is the most common cause of vitamin B12 deficiency in the UK
- a lack of these vitamins in your diet – this is uncommon, but can happen if you have a vegan diet, follow a fad diet or have a generally poor diet for a long time
- medicine – certain medicines, including anticonvulsants and proton pump inhibitors (PPIs), can affect how much of these vitamins your body absorbs
Both vitamin B12 deficiency and folate deficiency are more common in older people, affecting around 1 in 10 people aged 75 or over and 1 in 20 people aged 65 to 74.
Treating vitamin B12 or folate deficiency anaemia
Most cases of vitamin B12 and folate deficiency can be easily treated with injections or tablets to replace the missing vitamins.
Vitamin B12 supplements are usually given by injection at first.
Then, depending on whether your B12 deficiency is related to your diet, you’ll either require B12 tablets between meals or regular injections.
These treatments may be needed for the rest of your life.
Folic acid tablets are used to restore folate levels. These usually need to be taken for 4 months.
In some cases, improving your diet can help treat the condition and prevent it coming back.
Vitamin B12 is found in meat, fish, eggs, dairy products, yeast extract (such as Marmite) and specially fortified foods.
The best sources of folate include green vegetables, such as broccoli, brussels sprouts and peas.
Complications of vitamin B12 or folate deficiency anaemia
Although it’s uncommon, vitamin B12 or folate deficiency (with or without anaemia) can lead to complications, particularly if you have been deficient in vitamin B12 or folate for some time.
Potential complications can include:
- problems with the nervous system
- temporary infertility
- heart conditions
- pregnancy complications and birth defects
Adults with severe anaemia are also at risk of developing heart failure.
Some complications improve with appropriate treatment, but others, such as problems with the nervous system, can be permanent.W
Who Needs to See a Doctor or take a Vitamin B-12 Test?
Your body doesn’t naturally produce vitamin B-12. It comes from animal products like fish, meat, and dairy. People who are at risk for vitamin B-12 deficiency are:
- older adults
- strict vegetarians
- people with diabetes
- people who’ve had gastric bypass surgery
Some conditions may also affect your body’s ability to absorb B-12. Talk to your doctor if you have:
- pernicious anemia
- celiacc disease, where your body’s immune system reacts to gluten by damaging the lining of the intestine
- Crohn’s disease, an autoimmune condition that causes persistent inflammation of the gastrointestinal tract
- atrophic gastritis, a condition where your stomach lining narrows and limits stomach acid production
Medications that may also affect the body’s vitamin B-12 levels include:
- chloramphenicol, or Chloromycetin
- proton pump inhibitors, such as Prilosec and Prevacid
- H2 receptor blockers, such as Tagamet, Pepcid, and Zantac
- metformin, for diabetes